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 from the above link: 
Drugs induce changes in our body chemistry. These 
effect our body's function, metabolic processes. They influence how we 
feel, think and act, our personality, responses and reactions. These 
changes may be temporary but may also last
 a very long time. Some cause our DNA to be rewritten, which changes us 
quite tangibly into a different "us." Because the life of the flesh is 
in the blood (Leviticus 17:11) and our blood is subject to pharmakeia's 
effects, there is a direct impact on our souls! The influence is also 
supernatural, with the very real effect of opening a door or gateway, a 
dimensional portal through which demons may pass. Our thoughts and 
actions are then given over to their control. These entities are 
referred to as familiar spirits. The supernatural activity of angels and
 demons is the effectual power, which do work through natural agencies. 
Pharmakeia can hinder people from receiving the holy spirit, or can 
isolate those who have it from the Lord and deny them what benefit would
 otherwise be enjoyed.
Two Heads are Better than One
10 years ago